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SPARC at Purdue

MAPPING THE STOMACH’S NEURAL CIRCUITRY FOR STIMULATION


Stimulating Peripheral Activity to Relieve Conditions (SPARC) is an NIH-funded program aiming to advance neuromodulation therapies developed for precise neural control of end-organ system function to treat diseases and conditions.

The aim of our NIH-supported project is to consolidate and extend existing anatomical, molecular, and functional characterizations of the vagus-stomach connectome and identify optimal sites and parameters for disease-controlling vagal neuromodulation. We evaluate the functional measures for closed-loop feedback for bioelectronic management of gastric disorders, including gastroparesis, reflux disease, and eating disorders.

Participants

 

Resources

Browse the publically available SPARC data, presentations, and publications. The Resources section of this data-hub contains data sets, reports, experimental protocols, and other materials developed in the course of NIH-funded SPARC research. Please be aware that access to some sections may be restricted to the SPARC consortium investigators and the funding agency representatives.